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Buy B7-33 Peptide

B7-33 peptide is a synthetic analogue of the human relaxin-2 hormone, known for its therapeutic potential in cardiovascular health. It exhibits anti-fibrotic and anti-inflammatory properties, making it a valuable candidate in the treatment of conditions such as heart failure and fibrosis.

Buy B7-33 Peptide Vial

Which B7-33 Product is Right for You?

PharmaGrade Store New Zealand supplies a number of different B7-33 products to suit your research needs:

    • B7-33 Peptide Vial – Lyophilized B7-33, packaged in a sterile, glass vial for intramuscular injection into study participants’ muscles. Please note you also require bacteriostatic water to reconstitute the B7-33 peptide.
      Choose from 2mg or 6mg peptide vials here.
    • B7-33 Nasal Spray – a pre-mixed peptide solution ready for use into the nasal cavity of clinical research subjects. Choose from 15ml or 30ml nasal sprays here.
    • B7-33 Pre-Mixed Peptide Pen – Pen kits and refill cartridges come ready to use with pre-mixed B7-33 peptide and bacteriostatic water. Buy B7-33 2mg Pre-Mixed Pen here.

Buy B7-33 for Research Purposes

B7-33 peptide is a synthetic analogue derived from the human relaxin-2 hormone, designed to target specific pathways in cardiovascular health. It binds selectively to the Relaxin Family Peptide Receptor 1 (RXFP1), enabling regulation of vascular and tissue function [1].

Known for its anti-fibrotic and anti-inflammatory effects, B7-33 shows promise in treating heart failure, fibrosis, and related disorders. Compared to traditional relaxin therapies, New Zealand research professionals have found that B7-33 is more stable and simpler in structure. Furthermore, it is highly specific, enhancing its therapeutic potential [2].

Researchers are actively studying the relaxin peptide B7-33 through animal studies. Exploring its applications in innovative treatments, solidifying its role as a significant asset in medical and biotechnological advancements.

B7-33 Peptide Benefits

New Zealand Clinical studies have suggested that the B7-33 peptide could have the following potential benefits:

  • Potential cardiovascular benefits – B7-33 peptide has shown significant potential in treating cardiovascular conditions, especially heart failure, by improving vascular and tissue function [2].
  • B7-33 has displayed anti-fibrotic properties – In New Zealand clinical trials it effectively reduces the formation of fibrous tissue, making it a promising candidate for managing fibrosis-related diseases [2].
  • Anti-inflammatory benefits – B7-33 has been shown to have a significant impact on inflammation, contributing to its use in conditions associated with chronic inflammation, including the cardiovascular system and lung inflammation.

Scientific Research B7-33 New Zealand

B7-33 peptide is a synthetic analogue of the relaxin-2 hormone, which stands out in medical research for its therapeutic potential. By specifically targeting the Relaxin Family Peptide Receptor 1 (RXFP1), it enables precise regulation of vascular and tissue function. This selectivity has been pivotal in studies exploring its role in managing cardiovascular health, particularly heart failure, and fibrosis [2].

Furthermore, New Zealand research highlights its anti-fibrotic and anti-inflammatory properties, offering hope for conditions tied to excess tissue scarring and chronic inflammation. Preclinical studies and early trials have confirmed B7-33’s efficacy in reducing fibrosis and improving heart function. Its simplified structure and stability compared to traditional relaxin therapies enhance both safety and therapeutic potential [3].

Ongoing New Zealand clinical studies is now focused on expanding its application to additional inflammation-related conditions and chronic diseases. These findings position B7-33 as a powerful tool in biotechnology, with implications for developing safer, more effective treatments for complex cardiovascular and fibrotic diseases.

B7-33 Specifications:

View PharmaGrade Store New Zealand B7-33 HPLC Certificate here.

Amino Acid Sequence: VIKLSGRELVRAQIAISGMSTWS KRSL

Buy B7-33 Peptide New Zealand online for research use from PharmaGrade.Store today!

B7-33 Nasal Peptide Spray 15ml

Frequently Asked Questions about B7-33 Peptide New Zealand

Does B7-33 have side effects?

B7-33 is generally considered to have minimal side effects, especially compared to traditional treatments for cardiovascular conditions. However, as with any therapeutic peptide, it’s important to conduct thorough research and consult healthcare professionals before use. Since B7-33 is still under investigation, its long-term effects and safety profile are not fully established, and is sold for laboratory purposes only.

Can B7-33 help cardiac function?

B7-33 is a peptide that acts as a functionally selective agonist for the Relaxin Receptor. It has been shown to provide acute cardioprotection and limit adverse remodelling related to myocardial infarction by reducing cardiomyocyte death and endoplasmic reticulum stress. Additionally, B7-33 significantly reduces cardiac fibrosis and improves heart function, making it a promising therapeutic agent for cardiovascular diseases [1].

What effect can B7-33 have on blood pressure?

Extensive research has shown B7-33 to have effects on blood pressure, particularly in models of hypertension. It can normalize blood pressure and reduce proteinuria in certain hypertensive models, such as the DOCA rat model of preeclampsia. However, its therapeutic effects in some studies were found to be independent of blood pressure regulation, indicating that its primary benefits might not always be directly related to blood pressure changes.

Further Reading

Blogs:

Discover the revolutionary role of peptides in tissue repair and wound healing. Peptides, known their ability to stimulate angiogenesis, collagen production, and modulate immune responses. These bioactive compounds are crucial in promoting cell migration and growth, enhancing tissue regeneration, and preventing infections. The blog explores various peptide therapies, such as TB500 and BPC-157 blends, which accelerate healing by targeting specific cellular mechanisms. It also covers the potential of B7-33 for its ability to reduce inflammation and potentially improve tissue repair.

This article highlights the potential health benefits of the KPV peptide, a compound made of three amino acids: Lysine, Proline, and Valine. It emphasizes KPV’s anti-inflammatory and antioxidant properties, which can aid in reducing inflammation and oxidative stress. The peptide is also noted for enhancing skin elasticity by promoting collagen production, and regulating the immune system. The blog continues to discuss how peptides like KPV and B7-33 peptides could benefit cardiovascular health. Peptides could play a significant role in preventive health strategies.

Scientific Research:

[1] Devarakonda T, Mauro AG, Guzman G, Hovsepian S, Cain C, Das A, Praveen P, Hossain MA, Salloum FN. B7-33, a Functionally Selective Relaxin Receptor 1 Agonist, Attenuates Myocardial Infarction-Related Adverse Cardiac Remodeling in Mice. J Am Heart Assoc. 2020 Apr 21;9(8):e015748. 

[2] Alam F, Gaspari TA, Kemp-Harper BK, Low E, Aw A, Ferens D, Spizzo I, Jefferis AM, Praveen P, Widdop RE, Bathgate RAD, Hossain MA, Samuel CS. The single-chain relaxin mimetic, B7-33, maintains the cardioprotective effects of relaxin and more rapidly reduces left ventricular fibrosis compared to perindopril in an experimental model of cardiomyopathy. Biomed Pharmacother. 2023 Apr;160:114370. 

[3] Handley TNG, Praveen P, Tailhades J, Wu H, Bathgate RAD, Hossain MA. Further Developments towards a Minimal Potent Derivative of Human Relaxin-2. Int J Mol Sci. 2023 Aug 11;24(16):12670.

 

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DISCLAIMER: All products sold by PharmaGrade.Store are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals